Showing posts with label safety. Show all posts
Showing posts with label safety. Show all posts

Tuesday, March 6, 2012

UNREPORTED LAB ACCIDENTS MAKES FOR FALSE CLAIMS OF SAFETY IN LABS

Experts say US needs better tracking of lab accidents


 
Robert Roos News Editor


 
http://www.cidrap.umn.edu/cidrap/content/bt/bioprep/news/jan0512labsafe.html
 

Jan 5, 2012 (CIDRAP News) – In releasing safety guidelines today for workers in medical diagnostic laboratories, a panel of experts convened by the US Centers for Disease Control and Prevention (CDC) said the nation needs a system for "nonpunitive" surveillance and reporting of laboratory-acquired infections (LAIs).


 

Except for requirements in the CDC's Select Agent Program, which covers certain dangerous biological agents and toxins, such as Bacillus anthracis, there is no national system for reporting medical laboratory exposures and resulting infections, says the lengthy report.

 

"Because of the lack of an official surveillance mechanism for reporting LAIs and because of the fear of punitive action by an oversight agency if injuries are reported, the data needed to determine the extent and cause of LAIs are unavailable," the report states. "In addition, there is a dearth of science-based insights on prevention of LAIs."

 

 The panel calls for a "voluntary, nonpunitive surveillance and reporting system with the potential for anonymity to be implemented in the United States."

 

The comments are part of Guidelines for Safe Work Practices in Human and Animal Diagnostic Laboratories, which was released by the CDC as a supplement to Morbidity and Mortality Weekly Report. It was prepared by a "Biosafety Blue Ribbon Panel" of experts from the CDC and a number of university and private labs.

 

 The report is intended to supplement the fifth edition of Biosafety in Microbiological and Biomedical Laboratories, which was not specifically designed to address the routine operations of diagnostic labs in human and veterinary medicine.

 

The new guidelines are not designed to replace existing guidance, but have the general aims of improving safety in clinical labs, encouraging lab workers to think about safety issues they might not have considered, and encouraging them "to create and foster a culture of safety." The US Bureau of Labor Statistics estimates that workers in human and animal diagnostic labs number about 500,000, the report says.

 

 Given the shortage of solid data, the number of LAIs is unknown, but "Laboratory exposures occur more often than is generally suspected," the report says. It notes that hepatitis B has been the most frequent lab-acquired viral infection, with a rate of 3.5 to 4.6 cases per 1,000 workers, which is two to four times the rate in the general population.

 

 The five most common ways that lab workers acquire infections on the job, according to the guidelines, are:
  • Parenteral inoculations with syringe needles or other contaminated sharps
  • Pills and splashes onto skin and mucous membranes
  • Ingestion or exposure through mouth pipetting or touching mouth or eyes with fingers or contaminated objects
  • Animal bites and scratches (research laboratories or activities)
  • Inhalation of infectious aerosols

But the first four of those routes account for less than 20% of infections, the experts found. Studies over the years have shown that in many cases no specific exposure events were identified, which suggests that unsuspected infectious aerosols may play a large role in LAIs.

 
The guidelines address all functions of human and animal diagnostic labs, including microbiology, chemistry, hematology, and pathology. They include a specific section addressing veterinary lab issues not shared by human labs.

 
Recommendations intended for all laboratories include "use of Class IIA2 biological safety cabinets that are inspected annually; frequent hand washing; use of appropriate disinfectants, including 1:10 dilutions of household bleach"; risk assessments for many activities; written safety protocols that address chemical-related risks; the need for negative airflow into labs; and lab areas in which use of gloves is optional or recommended.

 
Each section of recommendations was reviewed by CDC experts and relevant national organizations, such as the College of American Pathologists, American Society for Microbiology, American Clinical Laboratory Association, Association of Public Health Laboratories, and several others, the report says.
 
CDC. Guidelines for Safe Work Practices in Human and Animal Diagnostic Laboratories: recommendations of a CDC-convened, Biosafety Blue Ribbon Panel. MMWR 2012 Jan 6;61(01):1-101 (supplement)

 

 

Saturday, February 25, 2012

Experimenting with Danger
http://www.csb.gov/videoroom/detail.aspx?VID=61

See the link above to a CSB video that highlights the lack of safety, regulations, and oversight in research laboratories in the United States.  With no obligatory uniform minimum standard of safety mandated for all research labs in the United States, serious injuries and deaths that could have been prevented continue to occur.  A serious lack of accountability and responsibility exist in the world of science.

Friday, April 9, 2010

Safety Lapses with Infected Biotech Worker at Defense Lab


Apr 6, 2010 6:26 pm US/Eastern
Army Finds Safety Lapses In Lab Infection Case


DAVID DISHNEAU, Associated Press Writer

HAGERSTOWN, Md. (AP) ― Army investigators at Fort Detrick recommended on Tueday that some laboratory safety procedures be reviewed after finding lapses in the case of a biodefense worker who became infected with tularemia, a potentially fatal respiratory disease.The woman survived the infection after a brief hospitalization at Walter Reed Army Medical Center in December.In an executive summary of an internal investigation, the U.S. Army Medical Research Institute of Infectious Diseases said the unidentified woman probably inhaled the bacteria between Nov. 13 and Nov. 17.Although there was no significant event investigators could point to, such as a spill or dropped flask, they cited several lapses in proper laboratory techniques that, taken together, may have increased her risk of exposure.The report said potentially contaminated waste wasn't placed in a cabinet designed to contain bacteria. Instead, it was deposited in a waste container inside the sealed laboratory suite.Even though she hadn't been voluntarily immunized with an experimental tularemia vaccine, the woman wasn't wearing a battery-powered device that delivers filtered air into a plastic hood, as required. Instead, she wore a half-face filter respirator. The less-protective device apparently was deemed sufficient because a blood test indicated she had developed antibodies to tularemia, perhaps due to a natural exposure in the past.The worker wasn't clear on the proper procedures for illness reporting, investigators found. She didn't immediately report her symptoms and when she did, on Nov. 23, she failed to immediately notify a second office, the institute's Special Immunizations Clinic, for an evaluation to determine if the illness could be work-related. She finally reported to the clinic on Dec. 1.The report's recommendations include a review of standard laboratory procedures for working with tularemia; a re-evaluation of policies for vaccination and the use of personal protective gear for tularemia; and formulation of an official policy for reporting illnesses and monitoring employee absences.
(© 2010 The Associated Press. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed.)

Monday, November 16, 2009

No Consequences to Breaking Safety Rules Results in Workers' Deaths

Sixteen workers are killed a day in the United States because of reckless negligence on the part of their employers. Under existing laws, these employers get a slap on the wrist, or walk away scot-free. Meanwhile, workers who blow the whistle face threats and retaliation at the workplace.
Click here for a link to a video called 16 Deaths Per Day.

Sunday, November 1, 2009

Public Trust in Public Health and Safety


Here is a link to a "must read", tongue in cheek article regarding public rights to public health and safety,.... or rather the lack of it. It is worth a read since it holds many truths about how our legal and regulatory systems are designed to enhanced unfettered corporate interests, crippling the public's trust and rights to public health and safety. Written by Carolyn Raffensperger...it is a winner.

Thursday, October 22, 2009

Violence in the Worker’s Compensation System-Desperate Times for Injured Workers

I would highly advise all worker’s who have been harmed by the Worker’s Compensation system NOT to walk into the worker’s compensation buildings toting a rifle like one angry man did yesterday, demanding help.

It won’t get you anywhere except in jail or in a straight jacket.

Unfortunately, injured workers find out too late, only after they are seriously injured, that the
WC system is broken, leaving many of them without adequate medical care, no avenue for future employment and without adequate compensation. Many injured workers become desperate and angry, realizing that the system has failed them and their future.

It can lead to desperate measures like the one took by this rifle-toting man, demanding help at gunpoint.

I am almost certain that every injured worker who has been mistreated by Worker’s Compensation can empathize with the struggles that this man must have endured to make him act so desperately. But his desperate act was not the right choice and it doesn’t help anyone. The way to solve the problem is not with violence but with unity.

The problem, however, is that there is no adequate organization that is currently available to help injured workers who are getting dumped on by the Worker’s Compensation system.

Injured workers around the world must show leadership and organize as a group. There is no other group that understands the problems beset within the Worker’s Compensation system better than the injured worker.



Injured Workers need to unite to help educate other workers about the real problems that exist. Injured Workers also need to support union representation to protect worker and public health and safety.

If injured workers do not unite, nothing will get accomplished. Desperate times and desperate measures will continue and injured workers will remain abandoned and mistreated as they are today.

http://www.thestar.com/news/canada/article/713574--9-may-be-held-by-edmonton-armed-man

http://www.nytimes.com/2009/03/31/nyregion/31comp.html

Wednesday, October 21, 2009

WATCHDOG ON SYTHETIC BIOLOGY

With the advent of our advanced biological-scientific age, there has never before in history been such a potential for both benefit and risk to humanity.

Many advanced biological endeavors such as nanotechnology, embryonic stem cell technologies, gene therapy and genetically engineered foods have moved into our lives with benefits promised but still to be discovered. Nevertheless, with the push to advance these technologies for discovery and profit and to endear them to the public, little research and money is given to understand the risks and threats that are inherent in developing these technologies. This is bad news for the public.

The dangers that these advanced technologies pose can impact our health, society and culture. Some of the health related threats to name a few are chronic illness, cancer and new emerging disease in humans and other species of life.

Within the past few years another new scientific advancement has been slowly emerging: Synthetic Biology.

Synthetic Biology is the science of creating new life, new biological systems and new biochemical pathways that are not found in nature. It can even create new pathogens.

Synthetic Biology employs a variety of interdisciplinary skills using microbiology, recombinant DNA technologies, bioinformatics, nanotechnology, biochemistry and cell biology.

As with other advanced technologies, synthetic biology is an open research field with little regulatory oversight to protect the public. It is another technology that the public needs to be concerned about as new advanced technologies are developed, patented and used on the public without appropriate risk management and public education.

Tuesday, February 10, 2009

SAFETY OR MONEY WHILE ON THE JOB? Do you have a choice?


In a statement in an article entitled, US Oil Workers Reach Wage Terms; Criticise Industry’s Overall Safety , the United Oil Workers said,

“Rather than launch a national strike over health and safety that would have hurt the American people at a time of economic crisis, the USW withdrew its health and safety proposal and focused on the economic package.”


Do you think that the United Steelworkers (USW) were ethically correct to focus their negotiations on their economic package while disregarding serious health and safety problems in the workplace?

Do you think in our dire times of economic woe that more and more employers will subject their workers to unsafe work conditions because they can?

Wednesday, January 7, 2009

STUDY SHOWS DANGEROUS BACTERIAL TOXIN TRANSFER HAS IMPLICATION TO PUBLIC HEALTH AND SAFETY AND GE RESEARCH

How can unregulated genetically engineering research lead to dangerous public health repercussions?

A recent study found that common viral parasites can act as secret conduits to transfer toxic and disease-causing genes from one bacteria species to an unrelated bacteria species. One serious public health concern from this discovery is the possibility that new emerging disease could develop through this viral method of DNA exchange between bacterial species. It also raises a red flag regarding public health and safety in genetic engineering (GE) research where all kinds of toxic and disease genes are cloned into bacteria used in plant and animal research. These GE genes could then possibly be transferred to other bacteria via a natural virus causing new emerging disease to humans and animals.

In the study noted above, scientists found that Staph aureus, a bacteria which is often associated with community and hospital acquired methicillin resistant staph aureus (MRSA) transferred its toxic shock genes to an unrelated bacterium, Listeria monocytogenes via a common virus called a bacteriophage. Listeria, itself, can cause a potentially deadly form of food poisoning while Staph can cause life-threatening diseases such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome and septicemia. The relatively high DNA transfer efficiency from Staph to Listeria suggests that other cases may very well exist in nature. This can have a major impact on human pathogenicity and new emerging disease. It also carries implications to tighten safety regulations upon the genetic engineering industry.

As mysterious chronic illness rises in our population, scientists and private industry remain to be unregulated in performing dangerous genetically engineered research. This unregulated research carries serious public health consequences and can create new emerging disease. The public should become better informed about this dangerous research, the unsafe work practices, and the lack of rights to scientists to file safety complaints.

Monday, February 11, 2008

Dangerous Genetic Technologies

Dangerous and unregulated laboratory practices in the United States are being performed at an alarming rate and unbeknownst to you, right in your own back yard. The risk is great especially in laboratories where genetically engineered viruses are being developed, for example, to create disease-state embryonic stem cells for biomedical research, drug discovery, gene therapy and bioweapons defense. This type of work is unregistered, unregulated and occurs in every major private and academic institute in the U.S. Accidental, negligent or intentional release of dangerous infectious genetic agents undeniably can contribute to new emerging disease in both humans and animals. As a professional who has worked extensively in this field and has witnessed unsafe laboratory practices, I truly believe that these advanced genetic biotechnologies may more than likely have already caused “mystery” illnesses in the human population. This is a public health threat that is being ignored.

Our current network of scientific communities have become so encrusted with big money from big Pharma that they have become handcuffed and blinded, unable to act at a level of integrity to advocate and protect the public health. Academics (even tenured full professors) are afraid to stand up against these powerful influences with the threat of loss of research money or threat of termination or blacklisting. In addition, our government has passed laws to financially link itself, like Siamese twins, to big Pharma in order to speed technology to market; and in doing so, has become part of the problem, not part of a solution.

As scientific advances are touted for their potential benefits and pushed upon the unsuspecting public, I hope this website will bring to the forefront the factors surrounding why the public threats and risks that being ignored. I hope eventually this will bring about change to increase public awareness, to invoke rights to biotech workers and to demand responsibility from the biomedical and academic communities who have left their post of guardian for public health and safety. In so being, this website will focus on the bioethical and safety issues and the political and economic influences related to biotechnology in hopes that it will contribute to educating at least a few more people to become “watchdogs on science”.

I encourage any input to this site, especially since I have little experience with blogs, but most importantly because you are a powerful and important part of the solution to this serious and troubling problem.

Monday, February 4, 2008

Dangerous Laboratory Opens

Top Secret Livermore Lab Opens
February 4, 2008

David Perlman, Chronicle Science Editor
A high-security laboratory where deadly microbes are being grown by scientists seeking defenses against terrorist attacks began operating in Livermore last week without public announcement, and opponents said Friday that they will go to federal court in an effort to close the facility down.
Built inside the closed campus of the Lawrence Livermore National Laboratory, the facility has been controversial ever since it was first proposed by homeland security officials more than five years ago. Tri-Valley CARES, the East Bay watchdog group that has long fought nuclear weapons research there, has led the fight against it with protests and legal actions.
The facility is known as a Biosafety-level 3 laboratory where highly trained workers, high-tech airlocks and extremely rigorous safety measures are required by federal rules in order to contain any of more than 40 potentially lethal disease-causing bacteria, viruses and fungi stored inside.
The National Nuclear Security Administration, an agency of the Energy Department, which oversees the Livermore site, announced Monday only that it had “granted approval” for Livermore to begin operating its new biosafety laboratory.
But the announcement did not disclose that the facility had already opened and that its scientists had begun working there the previous Friday - a fact that immediately outraged the lab’s opponents.
Robert Schwartz, the staff attorney for Tri-Valley CARES, said he will file suit in federal District Court next week to shut down the facility on the grounds that the final environmental impact statement published by the lab’s oversight agency was inadequate and that another supporting document was released without public hearings in violation of the Energy Department’s own rules.
In October, the Ninth District Court of Appeals in San Francisco had overruled an earlier federal court decision in support of the operation of the Livermore facility. The appeals court required officials to prepare a new environmental statement, including an assessment of the possibility that a suicide attack by terrorists could breach the facility’s walls and allow killer germs to spread beyond the lab.
In response, the security agency filed a document that said such an attack would be “highly unlikely,” and that it “found no significant impact” on the public or the environment from operations at the germ research facility.
A spokesman for the Energy Department’s nuclear security agency at Livermore told The Chronicle that its office manager approved the final revised environmental documents on Jan. 25, and that scientists began work at the lab the same day.
Asked why the press release on Monday did not disclose that the facility was already operating, the spokesman said “because we needed the time to physically copy the documents and place them in the public reading rooms as well as post them on the Web.”
Eric Gard, director of the new facility, said Friday his staff is now growing live cultures of many disease-causing organisms that could be used by terrorists in enemy biological warfare attacks and for which laboratory scientists will seek to develop countermeasures. Understanding the phenomenon of resistance to antibiotics is a high priority, he said.
Among the microbes held in the laboratory are bacteria that cause such highly dangerous and often deadly diseases as bubonic plague, anthrax, Rocky Mountain spotted fever, Q fever, tularemia and brucellosis or undulant fever, Gard said.
But scientists in his lab will also be researching other microbes unlikely to be used in terror attacks and that pose such major public health problems as tuberculosis, flu, and SARS, the severe acute respiratory syndrome that proved so deadly among elderly people in China, he said.
The scientists are barred by federal rules from conducting any research using germs for “potentially offensive use or purposes,” nor for the production of any bio-warfare weapons, according to the Energy Department.
Continuing its opposition to the Livermore facility by Tri-valley CARES, Marylia Kelley, the organization’s executive director, charged in a statement Friday that the lab and its sponsors “are jeopardizing the health and safety of the local community and the surrounding Bay Area.” Live anthrax germs grown in the lab and released into the air from the facility, even if it were only “lightly damaged” in a terrorist attack, for example, “could result in up to 9,000 deaths, depending on wind patterns,” Kelley maintained.
Consider this from a previous story:
Lab fined $450,000 for mishandling anthrax
A former Lawrence Livermore National Laboratory scientist who lacked proper credentials sent off an uninspected package containing two open vials of deadly pathogen anthrax across the country in 2005, triggering a $450,000 federal fine against the lab, authorities say.
The scientist, who resigned her post at the Livermore lab after the incident, left the twist caps off two containers and a loose cap on a third vial in a 1,025-vial shipment to Palm Beach, Fla., in September 2005, according to the findings of a federal agency’s review that led to the fine.
The lab in Florida then opened the anthrax shipment without proper precautions, and two of its workers were possibly exposed. The workers were treated with the antibiotic Cipro for a week, then returned to work.
A second shipment of about 3,000 vials made the next day by the same Lawrence Livermore scientist to a lab in Virginia had more vials than it should have, a separate violation of packaging restrictions. The scientist’s official credentials vouching for her ability to ship the pathogen had lapsed at the time of the shipments.
The fine was levied against the University of California - the former manager of the lab - as part of a recently reached negotiated settlement that became public at a congressional hearing about the safety of the government’s pathogen research programs. A key finding was that lab officials failed to inspect the shipments to ensure they were properly packaged and that labeling accurately reflected the contents.
Lab spokeswoman Susan Houghton said no anthrax leaked from the vials in the Florida shipment, and that the inner packaging would have trapped any anthrax if it had.
However, the government summary of the incident concluded: “During the transfers, anthrax was released from the shipped vials.”
Houghton said the lab has made a total of 30 shipments in the last six years without other incident. She noted that the 2005 case led to a seven-month shutdown of all the lab’s anthrax-related research for an audit, reorganization and retraining. In April 2006, the lab earned a three-year renewal of its registration to handle biological agents.
A citizen group, Tri-Valley CAREs, seized on the incident as an example of the danger to the community posed by the lab, as well as a new lab that has yet to open.
Marylia Kelley, the head of the group and who lives across from the lab, said lab officials “deliberately withheld important information” and lied about the magnitude of the incident, which was originally described as an inner packaging problem of an unnamed biological agent. It never mentioned anthrax.
“We now know that was a deception,” Kelley said in a statement. “The lab disclosed only one aspect of a major accident involving multiple violations of law and regulation and resulting in the release of a dangerous pathogen.”
Houghton said that with the renewal of its registration, the lab has a new oversight system, training and procedures. She said the federal Department of Transportation concluded the problem shipments amounted to “an isolated incident.”
“The registration allows our laboratory to continue necessary research on behalf of the nation,” the lab said in a statement.